Bleomycin-induced flagellate hyperpigmentation: A case report with review of literature

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منابع مشابه

Bleomycin‐induced flagellate hyperpigmentation

A 27-year old male with Hodgkin's lymphoma was treated with combined chemotherapy that included bleomycin. He presented with pruritic erythematous, edematous linear lesions and was diagnosed to have flagellate hyperpigmentation, a rare side effect of bleomycin chemotherapy.

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Bleomycin-induced flagellate hyperpigmentation.

Bleomycin is a chemotherapeutic agent used in the treatment of different tumours. It has several side effects, including flagellate hyperpigmentation, which is a unique and a well-documented side effect of bleomycin therapy. We report a case of a 23-year-old woman with a personal history of ovarian dysgerminoma, who developed flagellate hyperpigmentation on trunk after bleomycin therapy.

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Flagellate hyperpigmentation from bleomycin.

Sir, Mucocutaneous side effects associated with bleomycin are stomatitis, ulcers, scaly erythematous and bullous lesions, sclerosis, nail changes, digital gangrene and pigmentary alterations. Hyperpigmentation occurring mainly on the pressure areas of the skin as well as in areas of scratch marks is seen in approximately 30% of patients. Flagellate hyperpigmentation is very characteristic of bl...

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Flagellate Hyperpigmentation in a Scratched Area after Bleomycin for Pleurodesis A Case Report and Review of the Literature

269 From the Departments of Dermatology and Pathology, Veterans General Hospital-Kaohsiung and the Department of Dermatology, National Yang-Ming University, Taiwan Accepted for publication: June 26, 2006 Reprint requests: Ya-Hui Chen, M.D., Department of Dermatology, Veterans General Hospital-Kaohsiung, No 386, Ta-Chiung 1st Rd, Kaohsiung, Taiwan. TEL: 886-7-3422121 ext. 4304 FAX: 886-7-3468209...

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Bleomycin-induced flagellate erythema: A case report and review of the literature

Bleomycin has been used most commonly in the treatment of Hodgkin's lymphoma, certain germ cell tumors (GCT) and for the sclerosis of recurrent pleural effusions. Bleomycin toxicity predominantly affects the skin and lungs. Skin toxicity includes Raynaud's phenomenon, hyperkeratosis, nail-bed changes and palmoplantar desquamation. Flagellate erythema is an unusual rash occurring specifically du...

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ژورنال

عنوان ژورنال: Pigment International

سال: 2016

ISSN: 2349-5847

DOI: 10.4103/2349-5847.184260